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Testifying before a Senate committee in November, Dr. David Graham put the number in the United States who had suffered heart attacks or stroke as result of taking the arthritis drug Vioxx in the range of 88,000 to 139,000. As many as 40 percent of these people, or about 35,000-55,000, died as a result, Graham said. The unacceptable cardiovascular risks of Vioxx were evident as early as 2000 -- a full four years before the drug was finally withdrawn from the market by its manufacturer, Merck, according to a study released by The Lancet, the British medical journal. Merck says it disclosed all relevant evidence on Vioxx safety as soon as it acquired it, and pulled the drug as soon as it saw conclusive evidence of the drug's dangers.

Taken from THE 10 WORST CORPORATIONS OF 2004 By Russell Mokhiber and Robert Weissman .

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